ZED-1227 is an Orally Active and Specific Transglutaminase 2 Inhibitor for Intestinal Inflammation
Transglutaminases (TG) belong to a family of structurally and functionally related enzymes. These enzymes catalyse Ca2+-dependent post-translational modifications of proteins. Of these, Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase…