Midaglizole is a Potent α2-Adrenoceptor Antagonist with a Hypoglycemic Activity
α2-adrenoceptor is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. Besides, the α2-adrenoceptor not only inhibits the release of their neurotransmitters (autoreceptors) but can also regulate the…