TNP-470 is a Methionine Aminopeptidase-2 and Angiogenesis Inhibitor
Methionine aminopeptidase 2 (MetAP2), a member of the dimetallohydrolase family, is a cytosolic metalloenzyme that catalyzes the hydrolytic removal of N-terminal methionine residues from nascent proteins. Importantly, MetAP2 is found…