NIC-0102 is an Orally Active Proteasome Inhibitor, Specifically Inhibiting NLRP3 Inflammatory Vesicle Activation
Nucleotide oligomerization domain (NOD)-like receptors (NLRs) are critical cytoplasmic pattern-recognition receptors (PRRs). They play an important role in the host's innate immune response and immunity homeostasis. Among them, NLRP3 belongs…