Immune System Research - Up to date immunology information.

TAS6417 is a pan-Mutation Selective EGFR Inhibitor

2021-01-20 Edward Jenner

Despite dramatic response to first and second-generation EGFR TKIs, resistance emerges over time. The EGFR-T790M mutation accounts for more than…

2021-01-19 Edward Jenner

Neratinib is an irreversible tyrosine kinase inhibitor with IC50s of 59 nM and 92 nM for HER2 and EGFR, respectively.…

2021-01-18 Edward Jenner

Amino acids are essential for protein synthesis, they are supporting cell growth, and metabolism. System L belongs to the family…

2021-01-16 Edward Jenner

Epidermal growth factor receptor (EGFR) is a transmembrane protein and a member of the ErbB receptor family. Specifically, EGFR is…

2021-01-15 Edward Jenner

The HER protein is a transmembrane tyrosine kinase receptor and a member of the epidermal growth factor receptors (EGFRs) family.…