Blood Pressure - Immune System Research

Sparsentan (RE-021) is a Potent Dual Angiotensin II and Endothelin A Receptor Antagonist

The angiotensin II receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. Angiotensin II receptors include four subtypes: AT1, AT2, AT3 and AT4. They are…

Cardiovascular

BAY 73-1449 is a Selective Antagonist of Prostacyclin Receptor

Edward Jenner 2021-02-04

The prehepatic portal hypertensive rat is a model of human portal hypertension. It is widely used due to the fact that portosystemic shunting develops consistently. Bleeding from oesophageal varices is a…

Inflammation

GSK269962A is an Orally Active ROCK Inhibitor with Anti-Inflammatory and Vasodilatory Activities

Edward Jenner 2020-05-14

Rho kinase (ROCK) belongs to a family of Ser/Thr protein kinases. ROCK is an effector of the small GTPase Rho and belongs to the AGC family of kinases. ROCK has…

Sparsentan (RE-021) is a Potent Dual Angiotensin II and Endothelin A Receptor Antagonist

BAY 73-1449 is a Selective Antagonist of Prostacyclin Receptor

GSK269962A is an Orally Active ROCK Inhibitor with Anti-Inflammatory and Vasodilatory Activities

You Missed

PRX-08066 is an orally active 5-HT2BR Antagonist with Vasodilation Effect for PAH

Apocynin is a NADPH oxidase (NOX) Inhibitor for Metabolic and Inflammation Research

Xylometazoline is an α-adrenergic Receptor Agonist for Nose Stuffiness Research

Elafibranor is a PPARα/δ Agonist for Metabolic Disease Research