eIF2 (eukaryotic initiation factor 2), an eukaryotic initiation factor, is an essential factor for protein synthesis. eIF2 mediates the binding of tRNAiMet to the ribosome in a GTP-dependent manner. And…
Tumor necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins. This factor acts as a key mediator in autoimmune diseases such as rheumatoid arthritis and Crohn's…
Proteasomes control several cellular processes. They regulate protein degradation, mediate protein homeostasis. Proteasome function is tuned between a ubiquitously expressed constitutive proteasome and an immuno-optimized form, or immunoproteasome. The constitutive…