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Tag: Cancer

AB-680 is a CD73 Inhibitor for Cancer Immunotherapy

2019-05-24 Edward Jenner

CD73, known as ecto-5′-nucleotidase (ecto-5′-NT, EC 3.1.3.5) is a glycosyl-phosphatidylinositol (GPI)-linked 70-kDa cell surface enzyme found in most tissues.  Targeting…

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Posted in: Cancer Immunotherapy Filed under: Cancer, CD73

FT895 is a Potent and Selective HDAC11 Inhibitor

2019-05-09 Edward Jenner

Histone deacetylases (HDACs) control protein acetylation levels. HDACs catalyze the removal of acetyl groups that are responsible for the addition…

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Posted in: Cancer Immunology, Inflammation Filed under: Anti-Inflammatory, Cancer, HDAC

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