OXSI-2 is an Oxindole Syk Inhibitor
Spleen tyrosine kinase (Syk) is a 72 kDa non-receptor tyrosine kinase. Specifically, Syk is activated by binding the tandem SH2 domain to the immune receptor tyrosine activation motif (ITAM). Syk…
Spleen tyrosine kinase (Syk) is a 72 kDa non-receptor tyrosine kinase. Specifically, Syk is activated by binding the tandem SH2 domain to the immune receptor tyrosine activation motif (ITAM). Syk…
Omi/HtrA2 is a mammalian serine protease and has high homology to bacterial HtrA chaperones. This protease exhibits in mitochondria. And Omi also acts as a mitochondrial protein and it releases…
Caspase is a family of protease that plays an important role in programmed cell death. Specifically, caspase also has other definite roles in programmed cell death, such as apoptosis and…
Sigma Ligands has cytotoxic activity in vitro and is able to induce ceramide/caspase-independent apoptosis. In addition, these ligands down-regulate P-glycoprotein (P-gp) mRNA levels in some mouse and human models. In…
Influenza is one of the major plagues worldwide. Particularly, Influenza is a viral infection that attacks our respiratory system. Influenza A virus remains a major public health concern, both in…