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Tag: CDK8

BRD6989 Inhibits CDK8 and Upregulates IL-10

2020-11-19 Edward Jenner

Interleukin 10 (IL-10) is an anti-inflammatory cytokine. Specifically, IL-10 is a cytokine with multiple effects in immune regulation and inflammation.…

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Posted in: Inflammation Filed under: BRD6989, CDK8, IL-10, STAT

BRD6989 Inhibits CDK8 and Enhances IL-10 Production

2019-12-24 Edward Jenner

The cytokine IL-10 promotes immune homeostasis via multiple mechanisms. It includes suppressing inflammatory cytokine production by innate immune cells and…

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Posted in: Inflammation Filed under: CDK8, IL-10

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