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Tag: CFTR

Elexacaftor (VX-445) is a Modulator of CFTR

2021-09-11 Edward Jenner

Cystic fibrosis is a progressive, lethal, recessive genetic disease. Cystic fibrosis is caused by mutations affecting the CFTR gene localized…

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Posted in: Inflammation Filed under: Autophagy, CFTR

Icenticaftor (QBW251) is an Orally Active CFTR Channel Potentiator

2021-08-24 Edward Jenner

CFTR (Cystic fibrosis transmembrane conductance regulator) is a member of the ATP-Binding Cassette Transporter superfamily (ABCC7). And the CFTR exists…

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Posted in: Fibrosis Filed under: CFTR, COPD, Fibrosis
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