CHOP - Immune System Research

Ucf-101 is a Selective and Competitive Inhibitor of Pro-Apoptotic Protease Omi/HtrA2

Omi/HtrA2 is a mammalian serine protease and has high homology to bacterial HtrA chaperones. This protease exhibits in mitochondria. And Omi also acts as a mitochondrial protein and it releases…

Neuroimmunology

MK-28 is a Potent and Selective PERK Activator

Edward Jenner 2020-10-15

Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is an endoplasmic reticulum-associated stress sensor protein. PERK phosphorylates eukaryotic initiation factor 2α (eIF2α) to induce translation attenuation in response to ER…

Ucf-101 is a Selective and Competitive Inhibitor of Pro-Apoptotic Protease Omi/HtrA2

MK-28 is a Potent and Selective PERK Activator

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