Vilanterol (GW642444) is a potent, orally active and long-acting β2-AR (β2-adrenergic receptor) agonist with inherent 24-hour activity. The pEC50s for…
CFTR (Cystic fibrosis transmembrane conductance regulator) is a member of the ATP-Binding Cassette Transporter superfamily (ABCC7). And the CFTR exists…
PI3Kδ belongs to the class I Phosphoinositide 3-kinases (PI3Ks). PI3Kδ plays a critical role in chronic obstructive pulmonary disease (COPD).…
Matrix metallopeptidases (MMPs) are a kind of metalloproteinase which belongs to calcium-dependent zinc endopeptidase. Specifically, these enzymes can degrade all…
β2-adrenoreceptor is a kind of β-adrenergic receptor across the cell membrane, which binds to adrenaline. Specifically, Adrenaline is a kind…