Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Specifically, Coronavirus is one of the main pathogens that mainly target the human…
Sigma Ligands has cytotoxic activity in vitro and is able to induce ceramide/caspase-independent apoptosis. In addition, these ligands down-regulate P-glycoprotein (P-gp) mRNA levels in some mouse and human models. In…
Coronaviruses (CoV) are large plus-strand RNA viruses. They cause medical disorders such as the common cold, lower respiratory tract infections, and diarrhea. The SARS-CoV genome encodes a large polyprotein. Two…
The complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. Specifically, the complement system is a complex network, including the interaction…
The genetically diverse Orthocoronavirinae (coronavirus, CoV) family circulates in many avian and mammalian species. CoVs include four 4 genera: alpha (group 1), beta (group 2), gamma (group 3) and delta…