SX-682 is an Orally Active Inhibitor of CXCR1 and CXCR2
Recruitment of myeloid-derived suppressor cells (MDSCs) into tumors induces local immunosuppression in carcinomas. CXCR2+ neutrophilic MDSCs (PMN-MDSCs) are the most abundant myeloid cell subset within oral and lung syngeneic carcinomas….
