E3 Ligase Archives - Immune System Research

LS-102 is a Selective Synoviolin (Syvn1) Inhibitor

2020-04-14 Edward Jenner

Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease, affecting many people in the industrialized world. Synoviolin (Syvn1) is highly expressed in synoviocytes of patients with RA. Overexpression…

BC-1215, a FBXO3 Inhibitor, Reduces Severity of Cytokine-Driven Inflammation

2019-09-16 Edward Jenner

FBXOs (F-box proteins) is an F-box domain-containing proteins, mediate protein-protein interactions. They play a role in cellular functions, like signal transduction and cell cycle. Different mechanisms can regulate FBXO levels…

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Tag: E3 Ligase

LS-102 is a Selective Synoviolin (Syvn1) Inhibitor

2020-04-14 Edward Jenner

BC-1215, a FBXO3 Inhibitor, Reduces Severity of Cytokine-Driven Inflammation

2019-09-16 Edward Jenner