E3 Ligase - Immune System Research

LS-102 is a Selective Synoviolin (Syvn1) Inhibitor

Edward Jenner 2020-04-14

Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease, affecting many people in the industrialized world. Synoviolin (Syvn1) is highly expressed in synoviocytes of patients with RA. Overexpression…

Inflammation

BC-1215, a FBXO3 Inhibitor, Reduces Severity of Cytokine-Driven Inflammation

Edward Jenner 2019-09-16

FBXOs (F-box proteins) is an F-box domain-containing proteins, mediate protein-protein interactions. They play a role in cellular functions, like signal transduction and cell cycle. Different mechanisms can regulate FBXO levels…

LS-102 is a Selective Synoviolin (Syvn1) Inhibitor

BC-1215, a FBXO3 Inhibitor, Reduces Severity of Cytokine-Driven Inflammation

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