![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/BIO-1211-is-a-Highly-Selective-and-Orally-Active-α4β1-VLA-4-Inhibitor-2020-08-27.jpg)
Very Late Antigen-4 (VLA4 or CD49d/CD29) is aα4β1 integrin with a pivotal role in controlling immune cell migration into inflamed…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/JC-171-is-a-Selective-NLRP3-Inflammasome-Inhibitor-2020-08-05.jpg)
Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease of the central nervous system (CNS) and is a leading cause of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/09/ML604440-is-a-Specific-Proteasome-β1i-LMP2-Subunit-Inhibitor-2019-09-15.jpg)
The ubiquitin-proteasome system exerts numerous essential regulatory functions in almost all cell biological pathways. The 26S proteasome degrades polyubiquitylated protein…