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Tag: HNE

AE-3763 is a Peptide-Based Human Neutrophil Elastase Inhibitor

2020-12-23 Edward Jenner

Neutrophil elastase (HNE) is a serine protease, similar to chymotrypsin, and has a wide range of substrate specificity. Specifically, secreted…

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Posted in: Immunology, Inflammation Filed under: Edema, Elastase, HNE

BAY-678, An Orally Active HNE Inhibitor and a Chemical Probe Nominated by Structural Genomics Consortium

2019-03-27 Edward Jenner

Human neutrophil elastase (HNE) plays a pivotal role in matrix degradation. The protease shows high activity in inflammatory diseases. Accordingly,…

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Posted in: Inflammation Filed under: HNE, SGC
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