![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/11/Apilimod-is-a-Highly-Selective-PIKfyve-Inhibitor-2021-11-09.jpg)
Crohn disease, psoriasis, rheumatoid arthritis, multiple sclerosis and other chronic inflammatory diseases cause widespread and severe health problems. These and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/10/AB928-is-an-Orally-Active-Selective-Dual-A2aR-and-A2bR-Antagonist-2021-10-09.jpg)
Adenosine is generated through the hydrolysis of extracellular adenosine mono phosphate (AMP) by the ectonucleotidase CD73. It is an important…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/YM-341619-is-an-Orally-Active-STAT6-Inhibitor-2021-04-01.jpg)
Naive CD4+ T helper (Th) cells can differentiate into two distinct subsets, Th2 and Th1. Th2 cells produce IL-4, IL-5,…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/10/CL075-is-a-Selective-TLR8-Agonist-with-Immunomodulating-Properties-2020-11-03.jpg)
Toll-like receptors (TLRs) are a group of pattern recognition receptors for innate immune cells to detect various pathogen-associated molecular patterns.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/BIO-1211-is-a-Highly-Selective-and-Orally-Active-α4β1-VLA-4-Inhibitor-2020-08-27.jpg)
Very Late Antigen-4 (VLA4 or CD49d/CD29) is aα4β1 integrin with a pivotal role in controlling immune cell migration into inflamed…