![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/CU-115-is-a-Selective-TLR8-Antagonist-2021-02-03.jpg)
Nucleic acid (NA) sensors are part of the innate immune system. they can recognize multiple forms of intracellular self and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/G140-is-a-Potent-and-Selective-cGAS-Inhibitor-2020-09-16.jpg)
Innate immunity is the first-line cellular stress response. Additionally, it is a good way for defending the host cell against…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/CC-92480-is-a-Cereblon-E3-Ubiquitin-Ligase-Modulating-Drug-with-Antimyeloma-Activity-2019-12-10.jpg)
Immunomodulatory agents (IMiDs) are a class of immunomodulatory drugs. Thalidomide analogs have induced significant antimyeloma effects via immune-modulation, antiangiogenesis, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/10/Motolimod-is-a-Selective-TLR8-Agonist-2019-10-25.jpg)
Motolimod (VTX-2337) is a selective Toll-like receptor (TLR) 8 agonist. In vitro, HEK293 cells with various human TLRs, only Motolimod activates…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/08/BMS-986165-is-a-Highly-Selective-and-Orally-Active-TYK2-Inhibitor-for-Autoimmune-Diseases-Treatment-2019-08-20.jpg)
Janus kinases are non-receptor tyrosine kinases. In mammals, the family has four members, Jak1, Jak2, Jak3 and Tyrosine kinase 2…