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Tag: IL-12

GDC-046 is a Selective and Orally Bioavailable TYK2 Inhibitor

2020-07-15 Edward Jenner

Psoriasis and inflammatory bowel diseases (IBD), both of them are chronic inflammatory diseases. The characterizes of Psoriasis are mainly red…

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Posted in: Inflammation Filed under: IL-12, JAK, STAT, TYK

ZK 216348 is a Nonsteroidal Selective Glucocorticoid Receptor Agonist

2020-01-05 Edward Jenner

Glucocorticoids (GCs) are the most commonly used anti-inflammatory and immunosuppressive drugs.  GCs possess outstanding therapeutic effects, however, severe and sometimes…

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Posted in: Colitis Filed under: Anti-Inflammatory, GR, IL-12, Mineralocorticoid, Progesterone, TNF-α
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