![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/BIO-1211-is-a-Highly-Selective-and-Orally-Active-α4β1-VLA-4-Inhibitor-2020-08-27.jpg)
Very Late Antigen-4 (VLA4 or CD49d/CD29) is aα4β1 integrin with a pivotal role in controlling immune cell migration into inflamed…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/07/BMS-986251-is-an-Orally-Active-and-Selective-RORγt-Inverse-Agonist-2020-07-07.jpg)
Retinoic acid-related orphan receptor γt (RORγt) is a nuclear hormone receptor (NHR) and belongs to the RORγ family. It exists…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/08/SR0987-is-a-RORγt-Agonist-to-EnhanceP-rotectiveI-mmunity-2019-08-31.jpg)
The transcriptional activity of most nuclear receptors (NRs) can be modulated by small lipophilic molecules such as hormones, vitamins, steroids,…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/08/SR2211-is-a-Selective-RORγ-Inverse-Agonist-2019-08-29.jpg)
Retinoic acid receptor-related orphan receptors (RORs) are ligand-dependent transcriptional factors and members of the nuclear receptor superfamily. In fact, RORs…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/08/A-9758-is-a-Selective-RORγt-Inverse-Agonist-2019-08-29.jpg)
The retinoic acid-related orphan receptor (ROR) isoforms RORα (NR1F1), RORβ (NR1F2), and RORγ (NR1F3) are members of the steroid nuclear…