p53 - Immune System Research

GS143 is a Selective IκBα Ubiquitination Inhibitor

Edward Jenner 2020-09-01

GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. Firstly, when GS143 treatment at different doses in THP-1 cells. GS143 suppresses the…

Inflammation

AC-264613 is a Selective Protease-Activated Receptor (PAR-2) Agonist

Edward Jenner 2020-08-13

Proteinase activated receptor-2 (PAR-2) plays a crucial role in a wide variety of conditions with a strong inflammatory component. PAR-2 is an attractive target for drug discovery. Physiologically, PAR-2 receptors…

GS143 is a Selective IκBα Ubiquitination Inhibitor

AC-264613 is a Selective Protease-Activated Receptor (PAR-2) Agonist

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GS143 is a Selec­tive IκBα Ubiquitination Inhibitor

AC-264613 is a Selective Protease-Activated Receptor (PAR-2) Agonist

You Missed

Grazoprevir is a Hepatitis C virus NS3/4A Protease Inhibitor for Infection Research

Efbemalenograstim alfa is a Recombinant Fusion Protein for Neutropenia Research

Remibrutinib is an Orally Active BTK Inhibitor for Chronic Urticaria Research

Taurolidine is a Broad-spectrum Antimicrobial for Central Venous Catheter-Related Infections Research

GS143 is a Selective IκBα Ubiquitination Inhibitor