GS143 is a Selective IκBα Ubiquitination Inhibitor
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. Firstly, when GS143 treatment at different doses in THP-1 cells. GS143 suppresses the…