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Tag: PAM

MS48107 is a Selective GPR68 PAM

2020-12-26 Edward Jenner

G protein-coupled receptor 68 (GPR68) is originally discovered as a clinically related receptor in an ovarian cancer cell line. GPR68…

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Posted in: Neuroimmunology, Neurological Disease Filed under: GPR68, hERG, PAM

AZD7325 is an Orally Active GABAAα2,3 Positive Allosteric Modulator

2020-05-06 Edward Jenner

Benzodiazepines are useful in the research of anxiety disorders. Benzodiazepines also is useful for symptomatic relief of various anxiety states…

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Posted in: Epilepsy Filed under: Anxiety, Dravet, GABA, PAM

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