Dopamine Receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors.…
Dopamine D1 receptor is a G protein-coupled receptor that is one of the dopamine receptors. It exhibits cognitive functions such as memory and attention controlled by dopamine. Specifically, it regulates…
Striatal-enriched protein tyrosine phosphatase (STEP) is a CNS-rich protein associated with a variety of neurological and neuropsychiatric disorders. Firstly, it is expressed exclusively in the central nervous system. Then, it…
Double leucine zipper kinase (DLK, MAP3K12) and leucine zipper Carrying kinase (LZK, MAP3K13) are two homologous mitogen-activated protein kinases. They are regulators of neuronal apoptosis and axon degradation. And also…
Leucine Rich Repeat Kinase 2 (LRRK2) is a member of the leucine-rich repeat kinase family. Researchers found that the mutations in LRRK2 account for approximately 3-4% of Parkinson's disease patients.…