Humanized mouse models
Humanized mice, also known as 'Hu' mice, are generated through transplantation of human cells, tissues, or organs. But, there's a hitch. The mouse immune system often forcefully rejects these foreign…
Humanized mice, also known as 'Hu' mice, are generated through transplantation of human cells, tissues, or organs. But, there's a hitch. The mouse immune system often forcefully rejects these foreign…
The p38 MAPK pathway is a key regulatory factor for the biosynthesis of pro-inflammatory cytokines at the transcription and translation levels. There are four splicing variants in the p38 family:…
Toll-like receptors (TLRs) play a crucial role in the innate immune system by recognizing pathogen-related molecular patterns from various microorganisms. Specifically, TLRs signal by recruiting specific adaptor molecules, leading to…