Sulprostone is a Selective EP3 Receptor Agonist
Sulprostone (SHB 286), a potent PGE2 analogue, is one of the first EP3 selective agonists. While the half-life of PGE2 in vivo is extremely short, sulprostone (SHB 286) demonstrates an…
SC-58125 is a Potent and Selective COX-2 Inhibitor
Nonsteroidal anti-inflammatory agents (NSAIDs) are useful for the treatment of inflammatory diseases. In particular, NSAIDs inhibit the enzyme cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid to prostaglandins (PGs)…