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Tag: PPAR

SC-236 is an Orally Active COX-2 Specific Inhibitor

2020-11-24 Edward Jenner

Liver fibrosis is the accumulation of connective tissue in the liver. The consequence results from an imbalance between production and…

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Posted in: Fibrosis, Inflammation Filed under: ALSS, Anti-Fibrotic, COX-2, NSAID, PPAR

RSVA405 is a Potent and Orally Active AMPK Activator

2020-11-21 Edward Jenner

AMP-activated protein kinase (AMPK) is a central regulator of cellular and whole-body energy homeostasis. AMPK regulates cellular energy levels by…

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Posted in: Inflammation Filed under: Adipogenesis, Alzheimer's, AMPK, Autophagy, Ischemia, LDH, mTOR, PPAR, STAT3

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  • J-2156 is a Selective SST4 Receptor Agonist 2021-04-10
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  • TRV056 is a Gq-Biased Ligand of the Angiotensin II Receptor Type 1 (AT1R) 2021-04-07

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Anti-Inflammatory Anti-Tumor Antibacterial Antimalarial Antitumor Antiviral Apoptosis Autophagy Breast Cancer Btk Chemokines COPD COVID-19 COX Cytokine EGFR HBV HCV HDAC HIV IFN IL-6 IL-17 Infection Inflammasome Integrin Interferon Interleukin Leukemia Low Toxicity Multidrug Resistance Necroptosis NF-κB p38 MAPK PI3K Proteasome RIPK STAT STING T Cell Th17 TLR TNF TNF-α α4β1
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