PPI Archives - Immune System Research

SU3327 is a Potent, Selective and Competitive JNK Inhibitor

2020-03-25 Edward Jenner

The c-Jun N-terminal kinases (JNKs) are a series of serine/threonine protein kinases of the mitogen-activated protein kinase (MAPK) family. Besides, protein kinases comprise 2% of the mammalian genome and catalyze…

SP4206 is an IL-2/IL-2Rα Interaction Inhibitor

2020-02-22 Edward Jenner

Protein–protein interactions are major regulators of cell biology and important targets in drug discovery. Specifically, protein-protein interactions are driven by a small set of contact residues. Besides, small molecules that…

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SU3327 is a Potent, Selective and Competitive JNK Inhibitor

2020-03-25 Edward Jenner

SP4206 is an IL-2/IL-2Rα Interaction Inhibitor

2020-02-22 Edward Jenner