GNE684 is a Potent Cross-Species Inhibitor of RIP1
RIP1 is a crucial adaptor kinase on the crossroad of stress-induced signalling pathways and a cell's decision to live or die. Particularly, RIP1 acts in multiple signaling pathways to regulate…
RIP1 is a crucial adaptor kinase on the crossroad of stress-induced signalling pathways and a cell's decision to live or die. Particularly, RIP1 acts in multiple signaling pathways to regulate…
Receptor-interacting protein kinase 1 (RIPK1) is an important upstream kinase. Both scaffolding and kinase specific functions of RIPK1 can regulate inflammation. Recent work shows that active RIP1 kinase can drive…