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Tag: RORγt

FM26 is a Potent and Allosteric RORγt Inverse Agonist

2020-02-27 Edward Jenner

RORγt is a transcription factor of the RAR-related orphan nuclear receptor (ROR) family. It often expresses in Th17 cells and…

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Posted in: Autoimmune Disorders Filed under: IL-17a, RORγt

TMP920 is a Highly Potent and Selective RORγt Antagonist

2020-01-23 Edward Jenner

Th17 cells are third subset of CD4+ T effector cells in organ-specific autoimmunity. Th17 cells not only differ from Th1…

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Posted in: Autoimmune Disorders Filed under: RORγt, T Helper, T17
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