Etrasimod is a potent, selective, and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor. And the IC50 value is 1.88 nM in…
Sphingosine 1-phosphate (S1P) is a lysophosphatidic mediator, which can activate G protein-coupled sphingosine 1-phosphate receptor. Specifically, this leads to a…