SPPL2a - Immune System Research

SPL-707 is a Selective and Orally Available SPPL2a Inhibitor

Signal peptide peptidase-like 2a (SPPL2a) is a member of the signal peptide peptidase like protease (SPPL) family. Specifically, SPPL2a encodes lysosome/late endosomal membrane protein and has conserved active-site motifs "YD"…

Immunology

SPL-410 is an Orally Active SPPL2a Inhibitor

Edward Jenner 2019-08-01

The immune system is a powerful host defense mechanism specializing in antigen recognition. Besides, loss of tolerance to self-antigens results in pathological conditions which are manifested as autoimmune diseases. Moreover,…

SPL-707 is a Selective and Orally Available SPPL2a Inhibitor

SPL-410 is an Orally Active SPPL2a Inhibitor

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