![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/SPL-707-is-a-Selective-and-Orally-Available-SPPL2a-Inhibitor-2020-09-30.jpg)
Signal peptide peptidase-like 2a (SPPL2a) is a member of the signal peptide peptidase like protease (SPPL) family. Specifically, SPPL2a encodes…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/08/SPL-410-is-an-Orally-Active-SPPL2a-Inhibitor-2019-08-1.jpg)
The immune system is a powerful host defense mechanism specializing in antigen recognition. Besides, loss of tolerance to self-antigens results…