Glioblastoma (GBM) is the most common and most aggressive primary malignant brain tumour in adults, with a high morbidity, high…
Smoothened (Smo), a class Frizzled G protein-coupled receptor (class F GPCR), transduces the Hedgehog (Hh) signal across the cell membrane.…
Janus kinases (JAKs) are cytoplasmic tyrosine kinases. JAKs link cytokine signaling from membrane receptors to signal transducer and activator of…
AMP-activated protein kinase (AMPK) is a central regulator of cellular and whole-body energy homeostasis. AMPK regulates cellular energy levels by…