AS1810722 is an Orally Active STAT6 Inhibitor
Signal transducers and activators of transcription 6 (STAT6) is an important transcription factor in IL-4 signaling pathway. STAT6 is also a key regulator of the Th2 cell immune response. Therefore,…
YM-341619 is an Orally Active STAT6 Inhibitor
Naive CD4+ T helper (Th) cells can differentiate into two distinct subsets, Th2 and Th1. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, and control humoral immunity against parasites and…