![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/OP-5244-is-a-Potent-and-Orally-Bioavailable-CD73-Inhibitor-2020-10-13.jpg)
CD73, also known as 5′-nucleotidase (5′-NT), is commonly used to convert amp to adenosine. Specifically, CD73 is a surface enzyme…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/07/BD750-an-Effective-Immunosuppressant-is-a-JAK3-STAT5-Inhibitor-2020-07-28.jpg)
Interleukin-2 (IL-2) is a pleiotropic cytokine and controls the differentiation and homeostasis of both pro- and anti-inflammatory T cells. The…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/06/ZAP-180013-Inhibits-the-ZAP-70-SH2-and-Immunoreceptor-Tyrosine-Based-Activation-Motif-ITAMs-Interaction-2020-06-25.jpg)
ZAP-70 is a 70-kDa ζ-chain CD3 receptor protein tyrosine kinase that operates in the T-lymphocyte signalling pathways. The stimulation of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/BRD3308-a-Highly-Selective-HDAC3-Inhibitor-Activates-HIV-1-Transcription-and-Disrupts-HIV-1-Latency-2020-05-02.jpg){kind=spacer}
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl-lysine amino acid on a histone.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/GNE-1858-is-an-ATP-competitive-Hematopoietic-Progenitor-Kinase-1-HPK1-Inhibitor-2020-04-21.jpg)
Hematopoietic progenitor kinase-1 (HPK1) is a serine/threonine Ste20 related protein kinase. It expresses only in hematopoietic cells (such as T…