IBS008738 is a Potent TAZ Activator
The transcriptional coactivator with a PDZ-binding motif (TAZ, also called WWTR1) acts as an N-terminal TEAD-binding domain, one or two WW domains, and a transcriptional activation domain. The Hippo pathway…
The transcriptional coactivator with a PDZ-binding motif (TAZ, also called WWTR1) acts as an N-terminal TEAD-binding domain, one or two WW domains, and a transcriptional activation domain. The Hippo pathway…
The transcriptional enhanced associate domain (TEAD) is a transcription factor. In mammals, TEAD has four different isoforms namely TEAD1 (TEF-1/NTEF), TEAD2 (TEF-4/ETF), TEAD3 (TEF-5/ETFR-1), and TEAD4 (TEF-3/ETFR-2/FR-19). And there is…