![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/07/UCB-5307-is-An-TNF-Inhibitor-2022-0711.jpg)
Tumor necrosis factor (TNF, also referred to as TNFα) is a pro-inflammatory cytokine belonging to a family of trimeric proteins.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/COG1410-Exerts-Neuroprotective-and-Antiinflammatory-Effects-2020-01-11.jpg)
Apolipoprotein E (ApoE) is a protein involved in human fat metabolism. Specifically, ApoE belongs to a family of fat binding…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/HS271-is-a-Highly-Potent-Orally-Active-and-Selective-IRAK4-Inhibitor-2020-12-24.jpg)
IRAK-4 (interleukin-1 receptor-associated kinase 4) is a protein kinase involved in signal transduction of innate immune response from toll-like receptors.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/07/GSK717-is-a-Selective-NOD2-Nucleotide-Binding-Oligomerization-Domain-2-Inhibitor-2020-07-30.jpg)
NOD2 (nucleotide-binding oligomerization domain 2) is an intracellular pattern recognition receptor. NOD2 is one of cytoplasmic PRRs, and antigen-presenting cells…