Some Gram-negative pathogens have accumulated enough resistance mechanisms to render them virtually untreatable by modern antibacterial chemotherapy. A mainstay for…
The current epidemic of multidrug-resistant (MDR) bacterial infections is a critical challenge in health care today. A common mechanism of…
Staphylococcus aureus is a major bacterial human pathogen that causes a wide variety of clinical manifestations. Staphylococcus aureus is the…
Beta-lactamases are a family of enzymes involve in bacterial resistance to β-lactam antibiotics. Beta-lactamases act by breaking the beta-lactam ring…