![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/CMC2.24-is-an-Orally-Active-Tricarbonylmethane-Agent-2021-01-27.jpg)
RAS is the name of a series of related proteins commonly expressed in all cell lineages and organs. Specifically, RAS…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/TML-6-Inhibits-the-Synthesis-of-the-β-amyloid-Precursor-Proteina-nd-β-amyloid-2020-01-12.jpg)
Amyloid beta (Aβ) is a major component of amyloid plaques found in the brains of patients with Alzheimer’s disease. Specifically,…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/SP-100030-is-a-Potent-NF-κB-and-Activator-Protein-1-AP-1-Inhibitor-2020-10-01.jpg)
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors. The transcription factor NF-κB regulates multiple aspects of innate and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/GS143-is-a-Selective-IκBα-Ubiquitination-Inhibitor-2020-09-02.jpg)
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. Firstly, when GS143…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/01/MS417-is-a-BET-Specific-BRD4-Inhibitor-2020-01-17.jpg)
NF-κB-mediated inflammation is a major pathology in kidney diseases, such as non-kidney inflammatory diseases, and rheumatoid arthritis. HIV infection in…