![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/GSK-J4-is-a-Dual-Inhibitor-of-H3K27me3-me2-Demethylases-JMJD3-KDM6B-and-UTX-KDM6A-2021-02-18.jpg)
H3K27me3 is an epigenetic modification of DNA packaging protein histone H3. Specifically, it is a marker for the trimethylation of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/CU-115-is-a-Selective-TLR8-Antagonist-2021-02-03.jpg)
Nucleic acid (NA) sensors are part of the innate immune system. they can recognize multiple forms of intracellular self and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/IQ-3-is-a-Specific-JNK3-Inhibitor-2020-11-25.jpg)
Members of the activating protein 1 (AP-1) and nuclear factor-κB (NF-κB) families of transcription factors plays an important role in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/10/GSK356278-is-a-Selective-and-Orally-Bioavailable-PDE4-Inhibitor-2020-10-21.jpg)
Phosphodiesterase-4 (PDE4) acts as an intracellular non-receptor enzyme that modulates inflammation and epithelial integrity. GSK356278, a potent, selective, brain-penetrant phosphodiesterase…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/SP-100030-is-a-Potent-NF-κB-and-Activator-Protein-1-AP-1-Inhibitor-2020-10-01.jpg)
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors. The transcription factor NF-κB regulates multiple aspects of innate and…