H3K27me3 is an epigenetic modification of DNA packaging protein histone H3. Specifically, it is a marker for the trimethylation of…
Nucleic acid (NA) sensors are part of the innate immune system. they can recognize multiple forms of intracellular self and…
Members of the activating protein 1 (AP-1) and nuclear factor-κB (NF-κB) families of transcription factors plays an important role in…
Phosphodiesterase-4 (PDE4) acts as an intracellular non-receptor enzyme that modulates inflammation and epithelial integrity. GSK356278, a potent, selective, brain-penetrant phosphodiesterase…
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors. The transcription factor NF-κB regulates multiple aspects of innate and…