Toll-like receptors (TLRs) play a crucial role in the innate immune system by recognizing pathogen-related molecular patterns from various microorganisms.…
CD6, a surface glycoprotein of T cells, is a rheostat-type signalosome that tunes T cell activation. It belongs to the…
Serine proteases are the largest class of mammalian proteases. Serine proteases exist in all kingdoms of cellular life as well…
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase. Specifically, the enzyme is a key regulator of many signaling…
Crohn disease, psoriasis, rheumatoid arthritis, multiple sclerosis and other chronic inflammatory diseases cause widespread and severe health problems. These and…