MAPKs include many serine-threonine kinases. One of the major MAPK cascades is p38 MAPKs. p38 MAPK can serve as a potential therapeutic target for the treatment of not only inflammatory…
Osteoarthritis (OA) is a major global health burden. Osteoarthritis becomes an increasingly greater threat to human well-being at present. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides. There are…
Glucocorticoids (GCs) are the most commonly used anti-inflammatory and immunosuppressive drugs. GCs possess outstanding therapeutic effects, however, severe and sometimes irreversible side effects always accompany them. Therefore, it is urgent…