Malaria is an infectious disease. Malaria transmits to people through the bite of female Anophelesmosquitoes infected with Plasmodium falciparum or Plasmodium vivax. The disease still causes millions of people. The…
Sphingosine-1-phosphate (S1P) is a biologically active sphingolipid. It functions via the five G protein-coupled receptors (S1P1-S1P5). S1P1 plays a major role in regulating lymphocyte trafficking, exerting its immunomodulatory effect. A…
Hepatitis C virus (HCV) causes an infectious disease hepatitis C and primarily affects the liver. Patients often have mild or no obvious symptoms during the initial infection time. A fever,…
As is known, AGEs (Advanced glycation end products) are common ligands of RAGE. They play important role in diabetes complications, such as atherosclerosis, which is related to monocyte activation, adhesion,…
Human neutrophil elastase (HNE) plays a pivotal role in matrix degradation. The protease shows high activity in inflammatory diseases. Accordingly, HNE is promising applied in the treatment of pulmonary diseases…
Antibody-drug conjugates (ADCs) consist of a monoclonal antibody (mAb) linking to a cytotoxic payload via a linker. They are able to deliver potent chemotherapeutic agents to tumors in a targeted…
Human respiratory syncytial virus (RSV) is a single-stranded, negative-sense RNA virus belonging to the Paramyxoviridae family. Unfortunately, RSV usually causes childhood acute lower respiratory infection and produces severe disease at…