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Category: Pancreatitis

GSK180 is a Specific KMO Inhibitor for Acute Pancreatitis

2019-09-25 Edward Jenner

Systemic tryptophan metabolism in mammals occurs primarily via the kynurenine pathway. Tryptophan metabolites contribute to acute lung injury in rats…

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Posted in: Acute Pancreatitis, Inflammation, Pancreatitis Filed under: KMO

GSK2795039, a NOX2 Inhibitor, Inhibits ROS Production and NADPH Consumption

2019-08-14 Edward Jenner

NADPH oxidase (NOX) enzymes are major sources of reactive oxygen species (ROS). In particular, NOX mediates signaling events in a…

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Posted in: Acute Pancreatitis, Pancreatitis Filed under: Apoptosis, NADPH, NOX2, ROS

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