![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/03/CC-90001-is-a-selective-and-Orally-Active-Inhibitor-of-JNK-2021-03-10.jpg)
c-Jun N-terminal kinases (JNKs) belong to the mitogen-activated protein kinase family and are responsive to stress stimuli. Specifically, JNKs belong…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/TAK-615-is-a-LPA1-Receptor-Negative-Allosteric-Modulator-NAM-2020-12-03.jpg)
Lysophosphatidic acid (LPA) is a phospholipid growth factor that stimulates proliferation, chemotaxis, cation currents, and K+ currents in retinal pigment…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/SC-236-is-an-Orally-Active-COX-2-Specific-Inhibitor-2020-11-24.jpg)
Liver fibrosis is the accumulation of connective tissue in the liver. The consequence results from an imbalance between production and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/06/SHR0302-is-an-Orally-Active-and-Selective-JAK1-Inhibitor-2020-06-05.jpg)
Rheumatoid arthritis (RA) is a kind of destructive systemic autoimmune disease. Many different inflammatory cells invade the joint synovium. In…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/05/GSK-2793660-is-an-Orally-Active-Inhibitor-of-Cathepsin-C-CTSC-2020-05-21.jpg)
Cathepsin C (CTSC) acts as the key activator of the proenzymes of several neutrophil granule‐associated serine proteases (NSPs). CTSC also…