![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/TAK-615-is-a-LPA1-Receptor-Negative-Allosteric-Modulator-NAM-2020-12-03.jpg)
Lysophosphatidic acid (LPA) is a phospholipid growth factor that stimulates proliferation, chemotaxis, cation currents, and K+ currents in retinal pigment…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/SC-236-is-an-Orally-Active-COX-2-Specific-Inhibitor-2020-11-24.jpg)
Liver fibrosis is the accumulation of connective tissue in the liver. The consequence results from an imbalance between production and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/06/SHR0302-is-an-Orally-Active-and-Selective-JAK1-Inhibitor-2020-06-05.jpg)
Rheumatoid arthritis (RA) is a kind of destructive systemic autoimmune disease. Many different inflammatory cells invade the joint synovium. In…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/05/GSK-2793660-is-an-Orally-Active-Inhibitor-of-Cathepsin-C-CTSC-2020-05-21.jpg)
Cathepsin C (CTSC) acts as the key activator of the proenzymes of several neutrophil granule‐associated serine proteases (NSPs). CTSC also…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/05/CAY10471-is-a-Selective-and-Orally-Active-CRTH2-Antagonist-2020-05-06.jpg)
CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. In PC12 cells, CAY10471 blocks 15d-PGJ2-induced…