α2-adrenoceptor is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. Besides, the α2-adrenoceptor not only inhibits the…
Glucagon plays an important role in glucose metabolism. Upon hypoglycemia, pancreatic alpha cells can secrete glucagon which stimulates hepatic glucose…
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls the transcription of DNA, cytokine production…
Diabetes is a metabolic disease characterized by high blood sugar, which in turn is caused by a defect in insulin…
Osteoarthritis (OA) is a major global health burden. Osteoarthritis becomes an increasingly greater threat to human well-being at present. P2Y…