Skip to content

Immune System Research

Up to date immunology information

Immune System Research

Up to date immunology information

  • Home
    • Home
    • Inflammation
    • Auto-Inflammatory
Auto-Inflammatory Inflammation

BI 1015550 is an Orally Active PDE4B Inhibitor for Inflammation Research

Edward Jenner 2023-04-27

PDE4B is an enzyme that in humans is encoded by the PDE4B gene. Importantly, PDE4B is involved in dopamine-associated and stress-related behaviors. Particularly, study show that reduction in PDE4B activity…

Auto-Inflammatory Lung Inflammation

ACT-660602 is an Orally Active CXCR3 Antagonist

Edward Jenner 2022-09-08

CXCR3, which belongs to the transmembrane G protein-coupled receptor (GPCR) superfamily, is an inflammatory chemokine receptor. This chemokine receptor can regulate immune cell behavior and promote chemotaxis, cell adhesion as…

Auto-Inflammatory

CY-09 is a Selective and Direct NLRP3 Inhibitor for Inflammatory Disorders Treatment

Edward Jenner 2019-10-23

The inflammasomes are protein complexes. The innate immune sensors, including NOD-like receptor (NLR) family members (NLRP1, NLRP3, and NLRC4) as well as other non-NLR receptors form them.  Upon activation, the…

Auto-Inflammatory

GSK2983559 is a Specific and Oral Active RIP2 Kinase Inhibitor for Inflammatory Diseases

Edward Jenner 2019-09-01

The innate immune system is a key driver of our immune response from birth. It provides an immediate response to foreign invaders. It comprises pattern recognition receptors (PRRs). Toll-like receptors…

Auto-Inflammatory Inflammation

DB550, Targeting PLCγ1, Prevents Th17-driven Inflammation via Disrupting the CD95-PLCγ1 Interaction

Edward Jenner 2019-06-25

CD95L is a transmembrane ligand (m-CD95L) releases a soluble ligand (s-CD95L) that is cleaved by metalloproteases. Unlike m-CD95L, the interaction between s-CD95L and CD95 fails to recruit caspase-8 and FADD…

Arthritis Auto-Inflammatory

ONX-0914, a Selective Inhibitor of the Immunoproteasome Subunit LMP7, Attenuates Progression of Arthritis

Edward Jenner 2019-05-31

Immunoproteasome plays a critical role in the immune system because it degrades intracellular proteins, for example, those of viral origin, into small proteins. Immunoproteasome is abundantly expressed in immune cells.…

Auto-Inflammatory Innate Immune

PF-06928215 is a High Affinity Inhibitor of cGAS

Edward Jenner 2019-05-30

Interferons (IFNs) are a group of signaling proteins in response to the presence of several viruses. Cyclic GMP-AMP Synthase (cGAS, cGAMP synthase) is a cytosolic DNA sensor. Especially, cGAS activates…

Auto-Inflammatory Inflammation Innate Immune

C-176 is a Covalent Small Molecule Inhibitor of STING

Edward Jenner 2019-04-05

The abnormal activation of innate immune pathways partispate in the progress of various diseases. Unfortunately, the development of drugs specifically targeted molecules with interest and potential still remains challenging. A…

Recent Posts

  • Grazoprevir is a Hepatitis C virus NS3/4A Protease Inhibitor for Infection Research
  • Efbemalenograstim alfa is a Recombinant Fusion Protein for Neutropenia Research
  • Remibrutinib is an Orally Active BTK Inhibitor for Chronic Urticaria Research
  • Taurolidine is a Broad-spectrum Antimicrobial for Central Venous Catheter-Related Infections Research
  • Cabergoline is a D2-like Receptor Agonist for High Prolactin Levels Related Diseases

Archives

  • December 2023
  • November 2023
  • October 2023
  • September 2023
  • August 2023
  • July 2023
  • June 2023
  • May 2023
  • April 2023
  • March 2023
  • February 2023
  • January 2023
  • December 2022
  • November 2022
  • October 2022
  • September 2022
  • August 2022
  • July 2022
  • June 2022
  • May 2022
  • April 2022
  • March 2022
  • February 2022
  • January 2022
  • December 2021
  • November 2021
  • October 2021
  • September 2021
  • August 2021
  • July 2021
  • June 2021
  • May 2021
  • April 2021
  • March 2021
  • February 2021
  • January 2021
  • December 2020
  • November 2020
  • October 2020
  • September 2020
  • August 2020
  • July 2020
  • June 2020
  • May 2020
  • April 2020
  • March 2020
  • February 2020
  • January 2020
  • December 2019
  • November 2019
  • October 2019
  • September 2019
  • August 2019
  • July 2019
  • June 2019
  • May 2019
  • April 2019
  • March 2019
  • January 2019

Categories

  • Abdominal Aortic Aneurysm
  • Acanthosis
  • Achondroplasia
  • Acute Pancreatitis
  • Acute Radiation Syndrome
  • AIDs
  • Airway Immunology
  • Airway Inflammation
  • Allergy
  • Alzheimer
  • Alzheimer's disease
  • Analgesia
  • Anemia
  • antibiotic
  • Antibodydrug
  • anticonvulsant
  • Antigen-Induced Arthritis
  • Arterial Thrombosis
  • Arthritis
  • Asthma
  • Asthma
  • Atherosclerosis
  • Atopic Dermatitis
  • Atopic Dermatitis
  • Atopic dermatitis (AD)
  • Atrial Fibrillation
  • Autism
  • Auto-Inflammatory
  • Autoimmune diseases
  • Autoimmune Disorders
  • Autoimmune Encephalitis
  • Autoimmune Encephalomyelitis
  • Bacterial
  • Breast cancer
  • Bronchial Airway Infection
  • Cancer
  • Cancer Immunology
  • Cancer Immunotherapy
  • Cardiovascular
  • Chemokines
  • Chronic Arthritis
  • Chronic endemic diseases
  • Chronic Heart Failure
  • Chronic Hepatitis B
  • Chronic kidney disease
  • Chronic Liver Disease
  • Chronic lymphocytic leukemia (CLL)
  • Chronic Obstructive Pulmonary Disease
  • Chronic Obstructive Pulmonary Disease
  • Chronic obstructive pulmonary disease (COPD)
  • Chronic Urticaria
  • Cognitive Disorders
  • Colitis
  • Collagen-Induced Arthritis
  • Complement System
  • Coronavirus
  • Crohn's Disease
  • Degenerative disease
  • Diabetes
  • Diabetes
  • Diabetic Complication
  • Dilated cardiomyopathy disease
  • DNV
  • Dye
  • EMCV
  • Encephalomyelitis
  • Encephalomyelitis
  • Endocrinology
  • Endometriosis
  • Enterovirus
  • Epilepsy
  • Fabry Disease
  • Fibrosis
  • FIPV
  • Fungal
  • Fungal
  • glioblastoma
  • Graves' hyperthyroidism
  • Growth & Development
  • Haemophilia
  • HBV
  • HCV
  • Heart Failure
  • Hemorrhagic Disorder
  • Hepatic steatosis
  • Hepatic steatosis
  • Hepatitis
  • Hepatitis
  • Hepatitis C Virus
  • Hereditary Angioedema
  • HIV
  • Homeostasis
  • Hot flushes
  • HPV
  • HSV
  • hypertension
  • Idiopathic Pulmonary Fibrosis
  • Immune
  • Immune Checkpoint
  • Immune homeostasis
  • Immune Rejection
  • Immunity
  • Immunodeficiency
  • Immunology
  • Immunotherapy
  • Infection
  • Inflammation
  • Inflammatory
  • Influenza Virus
  • Innate Immune
  • Intestinal Inflammation
  • Ischemia
  • Ischemic stroke
  • Kidney Fibrosis
  • Kidney immune
  • Kidney Injury
  • Liver fibrosis
  • Lower Respiratory Infection
  • Lung Inflammation
  • Lupus Nephritis
  • lymphoma tumor
  • Malaria
  • Mesothelioma
  • Metabolic Disease
  • Metabolic Disorder
  • migraine
  • Multiple Sclerosis
  • Multiple Sclerosis
  • Myelodysplastic Syndromes
  • NAFLD
  • NASH
  • Neuroimmunology
  • Neurological Disease
  • Nociceptive
  • obesity
  • Osteoarthritis
  • Osteoporosis
  • Pancreatitis
  • Pancreatitis
  • Parasite
  • Parasite
  • Parkinson's disease
  • Parkinson’s
  • Patchy hair loss
  • Periodontitis
  • Peritonitis
  • Psoriasis
  • Psoriasis
  • Pulmonary Arterial Hypertension (PAH)
  • Pulmonary Fibrosis
  • RABV
  • RABV
  • Renal Fibrosis
  • Respiratory Infection
  • Retinal Vascular Disease
  • Retinal Vascular Diseases
  • Retinopathy
  • Rett Syndrome
  • Rheumatoid Arthritis
  • Rheumatoid Arthritis
  • Rhinitis
  • Rhinovirus
  • SARS
  • SARS-CoV
  • SARS-CoV-2
  • Schizophrenia
  • Schizophrenia
  • Seizure
  • Sepsis
  • Skin Inflammation
  • Stroke
  • Systemic Inflammatory Response Syndrome
  • Systemic Lupus Erythematosus
  • Systemic Scleroderma
  • T2DM
  • Thrombosis
  • Tuberculosis
  • Type 2 Diabetes Mellitus
  • Type 2 Diabetes Mellitus
  • Ulcerative Colitis
  • Uncategorized
  • Updated
  • Venous Ulcers
  • Viral Immunology

You Missed

Hepatitis Hepatitis C Virus

Grazoprevir is a Hepatitis C virus NS3/4A Protease Inhibitor for Infection Research

Breast cancer Infection

Efbemalenograstim alfa is a Recombinant Fusion Protein for Neutropenia Research

Cancer Chronic Urticaria Inflammatory Uncategorized

Remibrutinib is an Orally Active BTK Inhibitor for Chronic Urticaria Research

Infection

Taurolidine is a Broad-spectrum Antimicrobial for Central Venous Catheter-Related Infections Research

Immune System Research

Up to date immunology information

Copyright © All rights reserved | Blogus by Themeansar.