Interleukin-17 family (IL-17 family) is a pro-inflammatory cystine node cytokine family. After binding to the receptor, IL-17 can activate several…
RORγ (gene name RORC) is an orphan nuclear receptor (NR). Various metabolic processes regulate its expression and involvement. Meanwhile, RORγ…
The retinoic acid-related orphan receptor (ROR) isoforms RORα (NR1F1), RORβ (NR1F2), and RORγ (NR1F3) are members of the steroid nuclear…
BMS-582949 was identified as a highly selective p38α MAP kinase inhibitor as early in 2010. Moreover, it has entered into…
Janus kinases are non-receptor tyrosine kinases. In mammals, the family has four members, Jak1, Jak2, Jak3 and Tyrosine kinase 2…