Toll-like receptors 7 and 8 (TLR7/8) are receptors for single-stranded RNA that reside in the endosome. TLR8 mainly expresses in…
H3K27me3 is an epigenetic modification of DNA packaging protein histone H3. Specifically, it is a marker for the trimethylation of…
Tyrosine kinase 2 (Tyk2) is a non-receptor tyrosine kinase belonging to the Janus kinase (JAK) family. Specifically, the mammalian JAK…
SLE is a complex autoimmune inflammatory disease that affects multiple organs with unpredictable flares. Autoantibody/antigen immune-complexes in turn can activate…
Very Late Antigen-4 (VLA4 or CD49d/CD29) is aα4β1 integrin with a pivotal role in controlling immune cell migration into inflamed…