Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the COVID-19 pandemic. Although different small-molecule therapeutics…
Coronavirus disease 2019 (COVID-19) has caused a huge threat to global public health. Moreover, the constant emergence of variants of concern (VOCs) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…
Coronaviruses are a diverse group of viruses infecting many different animals, and they can cause mild to severe respiratory infections. In 2002 and 2012, respectively, two highly pathogenic coronaviruses with…
COVID-19 is an infectious disease caused by the coronavirus (SARS-CoV-2), which mainly causes symptoms such as fever and cough. It spreads through droplet transmission or contact transmission. Since 2019, COVID-19…
RdRp is a crucial viral enzyme in the life cycle of RNA viruses; hence, it has been targeted in various viral infections, including the HCV, the Zika virus (ZIKV), and…
Proteolytic enzymes are key regulators of human physiological processes. It is also essential for the replication of viruses, parasites, and bacteria causing infectious diseases. Cysteine proteases are drug targets because…