Ulcer is caused by discontinuity or break in a bodily membrane, which can damage normal function of the affected organ.…
Etrasimod is a potent, selective, and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor. And the IC50 value is 1.88 nM in…
NLRX1 is a highly conserved nucleotide-binding domain (NBD) and a member of the leucine-rich repeat (LRR) family (NLR). Specifically, NLRX1…
Tyrosine kinase 2 (Tyk2) is a non-receptor tyrosine kinase belonging to the Janus kinase (JAK) family. Specifically, the mammalian JAK…
Guanylyl cyclase-C (GC-C) is a transmembrane receptor for bacterial heat-stable enterotoxin and the mammalian peptides guanylin and uroguanylin. Guanylyl cyclase-C…